I had looping redirects, which gives the redirect unable to resolve this redirect message Farbor reported. Access log showed the file being requested 5 times, each one throwing a 301 redirect before the browser gives up.
However I cracked it, my problem was in my rewrite rules. I think I missed one of the 2.2 version rules when deleting and was throwing it into an infinite loop as wiping all the RewriteRule and putting them in again seems to have solved it. I just got over-excited by someone reporting the same basic error and assumed I'd made the same mistake, when apparently I can make new and way dafter ones all by myself :)
Fixed for me, it was a sloppy upgrade on my behalf.